Insulin Promotes Mitochondrial Respiration and Survival through PI3K/AKT/GSK3 Pathway in Human Embryonic Stem Cells

Insulin is an essential growth factor for the survival and self-renewal of human embryonic stem cells (hESCs). Although it is best known as the principal hormone promoting glycolysis in somatic cells, insulin's roles in hESC energy metabolism remain unclear. In this report, we demonstrate that...

Descripción completa

Detalles Bibliográficos
Autores principales: Ren, Zhili, Zhong, Hui, Song, Chengcheng, Deng, Chunhao, Hsieh, Hsun-Ting, Liu, Weiwei, Chen, Guokai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724469/
https://www.ncbi.nlm.nih.gov/pubmed/33186539
http://dx.doi.org/10.1016/j.stemcr.2020.10.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724469/
https://www.ncbi.nlm.nih.gov/pubmed/33186539
http://dx.doi.org/10.1016/j.stemcr.2020.10.008

Ejemplares similares