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An In Vitro Differentiation Protocol for Human Embryonic Bipotential Gonad and Testis Cell Development
Currently an in vitro model that fully recapitulates the human embryonic gonad is lacking. Here we describe a fully defined feeder-free protocol to generate early testis-like cells with the ability to be cultured as an organoid, from human induced pluripotent stem cells. This stepwise approach uses...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724470/ https://www.ncbi.nlm.nih.gov/pubmed/33217324 http://dx.doi.org/10.1016/j.stemcr.2020.10.009 |