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The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation

Chromatin regulators play fundamental roles in controlling pluripotency and differentiation. We examined the effect of mutations in 703 genes from nearly 70 chromatin-modifying complexes on human embryonic stem cell (ESC) growth. While the vast majority of chromatin-associated complexes are essentia...

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Detalles Bibliográficos
Autores principales: Lezmi, Elyad, Weissbein, Uri, Golan-Lev, Tamar, Nissim-Rafinia, Malka, Meshorer, Eran, Benvenisty, Nissim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724477/
https://www.ncbi.nlm.nih.gov/pubmed/32559458
http://dx.doi.org/10.1016/j.stemcr.2020.05.014