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The Chromatin Regulator ZMYM2 Restricts Human Pluripotent Stem Cell Growth and Is Essential for Teratoma Formation
Chromatin regulators play fundamental roles in controlling pluripotency and differentiation. We examined the effect of mutations in 703 genes from nearly 70 chromatin-modifying complexes on human embryonic stem cell (ESC) growth. While the vast majority of chromatin-associated complexes are essentia...
Autores principales: | Lezmi, Elyad, Weissbein, Uri, Golan-Lev, Tamar, Nissim-Rafinia, Malka, Meshorer, Eran, Benvenisty, Nissim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724477/ https://www.ncbi.nlm.nih.gov/pubmed/32559458 http://dx.doi.org/10.1016/j.stemcr.2020.05.014 |
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