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Transcriptional response modules characterise IL-1β and IL-6 activity in COVID-19

Dysregulated IL-1β and IL-6 responses have been implicated in the pathogenesis of severe Coronavirus Disease 2019 (COVID-19). Innovative approaches for evaluating the biological activity of these cytokines in vivo are urgently needed to complement clinical trials of therapeutic targeting of IL-1β an...

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Detalles Bibliográficos
Autores principales: Bell, Lucy CK, Meydan, Cem, Kim, Jacob, Foox, Jonathan, Butler, Daniel, Mason, Christopher E., Shapira, Sagi D., Noursadeghi, Mahdad, Pollara, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724660/
https://www.ncbi.nlm.nih.gov/pubmed/33299992
http://dx.doi.org/10.1101/2020.07.22.202275