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Amilorides inhibit SARS-CoV-2 replication in vitro by targeting RNA structures

The SARS-CoV-2 pandemic, and the likelihood of future coronavirus pandemics, has rendered our understanding of coronavirus biology more essential than ever. Small molecule chemical probes offer to both reveal novel aspects of virus replication and to serve as leads for antiviral therapeutic developm...

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Detalles Bibliográficos
Autores principales: Martina, Zafferani, Christina, Haddad, Le, Luo, Jesse, Davila-Calderon, Liang, Yuan-Chiu, Christian, Shema Mugisha, Monaghan, Adeline G., Kennedy, Andrew A., Yesselman, Joseph D., Gifford, Robert R., Tai, Andrew W., Kutluay, Sebla B., Li, Mei-Ling, Brewer, Gary, Tolbert, Blanton S., Hargrove, Amanda E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724665/
https://www.ncbi.nlm.nih.gov/pubmed/33299997
http://dx.doi.org/10.1101/2020.12.05.409821