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Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity

SARS-CoV-2 infection triggers highly variable host responses and causes varying degrees of illness in humans. We sought to harness the peripheral blood mononuclear cell (PBMC) response over the course of illness to provide insight into COVID-19 physiology. We analyzed PBMCs from subjects with variab...

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Detalles Bibliográficos
Autores principales: Giroux, Nicholas S., Ding, Shengli, McClain, Micah T., Burke, Thomas W., Petzold, Elizabeth, Chung, Hong A., Palomino, Grecia R., Wang, Ergang, Xi, Rui, Bose, Shree, Rotstein, Tomer, Nicholson, Bradly P., Chen, Tianyi, Henao, Ricardo, Sempowski, Gregory D., Denny, Thomas N., Ko, Emily R., Ginsburg, Geoffrey S., Kraft, Bryan D., Tsalik, Ephraim L., Woods, Christopher W., Shen, Xiling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724678/
https://www.ncbi.nlm.nih.gov/pubmed/33300002
http://dx.doi.org/10.1101/2020.12.04.412155