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KMT2A/C mutations function as a potential predictive biomarker for immunotherapy in solid tumors

Epigenetic factors play important roles in tumor immunology. Histone-lysine N-methyltransferase 2 (KMT2) family genes exert histone H3 methylation, but its role in immunotherapy remains unclear. Our study is the first to investigate the correlation between KMT2 gene mutations and the clinical benefi...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Wu, Hao-Xiang, Xu, Ming, Xie, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724704/
https://www.ncbi.nlm.nih.gov/pubmed/33298164
http://dx.doi.org/10.1186/s40364-020-00241-0