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4-Hydroxyisoleucine relieves inflammation through iRhom2-dependent pathway in co-cultured macrophages and adipocytes with LPS stimulation

BACKGROUND: 4-Hydroxyisoleucine (4-HIL) is an active ingredient extracted from Trigonella foenum-graecum L., a Chinese traditional herbal medicine, which exerts the efficacy of anti-obesity and anti-diabetes. We previously reported that 4-HIL potentiates anti-inflammatory and anti-insulin resistance...

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Detalles Bibliográficos
Autores principales: Zhou, Cong, Chen, Rui, Gao, Feng, Zhang, Jiaoyue, Lu, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724822/
https://www.ncbi.nlm.nih.gov/pubmed/33298044
http://dx.doi.org/10.1186/s12906-020-03166-1