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Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer’s disease and implicate its dynamic role in disease progression

BACKGROUND: While Alzheimer’s disease (AD) remains one of the most challenging diseases to tackle, genome-wide genetic/epigenetic studies reveal many disease-associated risk loci, which sheds new light onto disease heritability, provides novel insights to understand its underlying mechanism and pote...

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Detalles Bibliográficos
Autores principales: Wang, Qi, Chen, Yinghua, Readhead, Benjamin, Chen, Kewei, Su, Yi, Reiman, Eric M., Dudley, Joel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724832/
https://www.ncbi.nlm.nih.gov/pubmed/33298155
http://dx.doi.org/10.1186/s13148-020-00984-5