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Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees
BACKGROUND: There were scarcely germline variants of familial lung cancer (LC) identified. We conducted an study with whole-exome sequencing of pedigrees with familial lung cancer to analyze the potential genetic susceptibility. METHODS: Probands with the highest hereditary background were identifie...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724858/ https://www.ncbi.nlm.nih.gov/pubmed/33297998 http://dx.doi.org/10.1186/s12885-020-07528-3 |