Germline variation networks in the PI3K/AKT pathway corresponding to familial high-incidence lung cancer pedigrees

BACKGROUND: There were scarcely germline variants of familial lung cancer (LC) identified. We conducted an study with whole-exome sequencing of pedigrees with familial lung cancer to analyze the potential genetic susceptibility. METHODS: Probands with the highest hereditary background were identifie...

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Detalles Bibliográficos
Autores principales: Lin, Huan, Zhang, Gong, Zhang, Xu-chao, Lian, Xin-lei, Zhong, Wen-zhao, Su, Jian, Chen, Shi-liang, Wu, Yi-long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724858/
https://www.ncbi.nlm.nih.gov/pubmed/33297998
http://dx.doi.org/10.1186/s12885-020-07528-3

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