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DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections

The molecular mechanisms underlying HIV-induced inflammation, which persists even during effective long-term treatment, remain incompletely defined. Here, we studied pathogenic and nonpathogenic simian immunodeficiency virus (SIV) infections in macaques and African green monkeys, respectively. We lo...

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Detalles Bibliográficos
Autores principales: Jochems, Simon P., Jacquelin, Beatrice, Tchitchek, Nicolas, Busato, Florence, Pichon, Fabien, Huot, Nicolas, Liu, Yi, Ploquin, Mickaël J., Roché, Elodie, Cheynier, Rémi, Dereuddre-Bosquet, Nathalie, Stahl-Henning, Christiane, Le Grand, Roger, Tost, Jorg, Müller-Trutwin, Michaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724887/
https://www.ncbi.nlm.nih.gov/pubmed/33298174
http://dx.doi.org/10.1186/s13148-020-00971-w