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Relationship between MUTYH, OGG1 and BRCA1 mutations and mRNA expression in breast and ovarian cancer predisposition

The aetiology of breast and ovarian cancer (BC/OC) is multi-factorial. At present, the involvement of base excision repair (BER) glycosylases (MUTYH and OGG1) in BC/OC predisposition is controversial. The present study investigated whether germline mutation status and mRNA expression of two BER gene...

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Detalles Bibliográficos
Autores principales: Moscatello, Carmelo, Di Nicola, Marta, Veschi, Serena, Di Gregorio, Patrizia, Cianchetti, Ettore, Stuppia, Liborio, Battista, Pasquale, Cama, Alessandro, Curia, Maria Cristina, Aceto, Gitana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725208/
https://www.ncbi.nlm.nih.gov/pubmed/33343895
http://dx.doi.org/10.3892/mco.2020.2177