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Dichotomous Engagement of HDAC3 Activity Governs Inflammatory Responses

Histone deacetylase 3 (HDAC3) is unique among the HDAC superfamily of chromatin modifiers that silence transcription through enzymatic modification of histones because interaction with nuclear receptor corepressors (NCoR1/2) is required for engagement of its catalytic activity(1–3). However, loss of...

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Detalles Bibliográficos
Autores principales: Nguyen, Hoang C. B., Adlanmerini, Marine, Hauck, Amy K., Lazar, Mitchell A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725280/
https://www.ncbi.nlm.nih.gov/pubmed/32760002
http://dx.doi.org/10.1038/s41586-020-2576-2