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PET imaging and pharmacological therapy targeting carbonic anhydrase-IX high-expressing tumors using US2 platform based on bivalent ureidosulfonamide

Carbonic anhydrase-IX (CA-IX) is attracting much attention as a target molecule for cancer treatment since high expression of CA-IX can lead to a poor prognosis of patients. We previously reported low-molecular-weight (111)In/(90)Y complexes with a bivalent ureidosulfonamide scaffold ([(111)In/(90)Y...

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Detalles Bibliográficos
Autores principales: Iikuni, Shimpei, Watanabe, Hiroyuki, Shimizu, Yoichi, Nakamoto, Yuji, Ono, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725290/
https://www.ncbi.nlm.nih.gov/pubmed/33296398
http://dx.doi.org/10.1371/journal.pone.0243327