Azithromycin resistance mutations in Streptococcus pneumoniae as revealed by a chemogenomic screen

We report on the combination of chemical mutagenesis, azithromycin selection and next-generation sequencing (Mut-Seq) for the identification of small nucleotide variants that decrease the susceptibility of Streptococcus pneumoniae to the macrolide antibiotic azithromycin. Mutations in the 23S riboso...

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Detalles Bibliográficos
Autores principales: Gingras, Hélène, Patron, Kévin, Leprohon, Philippe, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725334/
https://www.ncbi.nlm.nih.gov/pubmed/33074087
http://dx.doi.org/10.1099/mgen.0.000454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725334/
https://www.ncbi.nlm.nih.gov/pubmed/33074087
http://dx.doi.org/10.1099/mgen.0.000454

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