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Azithromycin resistance mutations in Streptococcus pneumoniae as revealed by a chemogenomic screen
We report on the combination of chemical mutagenesis, azithromycin selection and next-generation sequencing (Mut-Seq) for the identification of small nucleotide variants that decrease the susceptibility of Streptococcus pneumoniae to the macrolide antibiotic azithromycin. Mutations in the 23S riboso...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Microbiology Society
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725334/ https://www.ncbi.nlm.nih.gov/pubmed/33074087 http://dx.doi.org/10.1099/mgen.0.000454 |