Population variability in the generation and selection of T-cell repertoires

The diversity of T-cell receptor (TCR) repertoires is achieved by a combination of two intrinsically stochastic steps: random receptor generation by VDJ recombination, and selection based on the recognition of random self-peptides presented on the major histocompatibility complex. These processes le...

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Detalles Bibliográficos
Autores principales: Sethna, Zachary, Isacchini, Giulio, Dupic, Thomas, Mora, Thierry, Walczak, Aleksandra M., Elhanati, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725366/
https://www.ncbi.nlm.nih.gov/pubmed/33296360
http://dx.doi.org/10.1371/journal.pcbi.1008394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725366/
https://www.ncbi.nlm.nih.gov/pubmed/33296360
http://dx.doi.org/10.1371/journal.pcbi.1008394

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