Digital-WGS: Automated, highly efficient whole-genome sequencing of single cells by digital microfluidics

Single-cell whole-genome sequencing (WGS) is critical for characterizing dynamic intercellular changes in DNA. Current sample preparation technologies for single-cell WGS are complex, expensive, and suffer from high amplification bias and errors. Here, we describe Digital-WGS, a sample preparation p...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Qingyu, Ruan, Weidong, Lin, Xiaoye, Wang, Yang, Zou, Fenxiang, Zhou, Leiji, Zhu, Zhi, Yang, Chaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725457/
https://www.ncbi.nlm.nih.gov/pubmed/33298451
http://dx.doi.org/10.1126/sciadv.abd6454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725457/
https://www.ncbi.nlm.nih.gov/pubmed/33298451
http://dx.doi.org/10.1126/sciadv.abd6454

Ejemplares similares