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Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography

Subcellular neighborhoods, comprising specific ratios of organelles and proteins, serve a multitude of biological functions and are of particular importance in secretory cells. However, the role of subcellular neighborhoods in insulin vesicle maturation is poorly understood. Here, we present single-...

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Detalles Bibliográficos
Autores principales: Zhang, Xianjun, Carter, Stephen D., Singla, Jitin, White, Kate L., Butler, Peter C., Stevens, Raymond C., Jensen, Grant J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725471/
https://www.ncbi.nlm.nih.gov/pubmed/33298442
http://dx.doi.org/10.1126/sciadv.abc8258