AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9

The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key component of the nuclear envelope MTOC. In rat cardiomyocytes, AKAP6 anchors centrosomal proteins to the nuclear envelope through it...

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Detalles Bibliográficos
Autores principales: Vergarajauregui, Silvia, Becker, Robert, Steffen, Ulrike, Sharkova, Maria, Esser, Tilman, Petzold, Jana, Billing, Florian, Kapiloff, Michael S, Schett, George, Thievessen, Ingo, Engel, Felix B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725499/
https://www.ncbi.nlm.nih.gov/pubmed/33295871
http://dx.doi.org/10.7554/eLife.61669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725499/
https://www.ncbi.nlm.nih.gov/pubmed/33295871
http://dx.doi.org/10.7554/eLife.61669

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