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AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9
The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key component of the nuclear envelope MTOC. In rat cardiomyocytes, AKAP6 anchors centrosomal proteins to the nuclear envelope through it...
Autores principales: | Vergarajauregui, Silvia, Becker, Robert, Steffen, Ulrike, Sharkova, Maria, Esser, Tilman, Petzold, Jana, Billing, Florian, Kapiloff, Michael S, Schett, George, Thievessen, Ingo, Engel, Felix B |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725499/ https://www.ncbi.nlm.nih.gov/pubmed/33295871 http://dx.doi.org/10.7554/eLife.61669 |
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