Cargando…
Evolved bacterial resistance against fluoropyrimidines can lower chemotherapy impact in the Caenorhabditis elegans host
Metabolism of host-targeted drugs by the microbiome can substantially impact host treatment success. However, since many host-targeted drugs inadvertently hamper microbiome growth, repeated drug administration can lead to microbiome evolutionary adaptation. We tested if evolved bacterial resistance...
Autores principales: | Rosener, Brittany, Sayin, Serkan, Oluoch, Peter O, García González, Aurian P, Mori, Hirotada, Walhout, Albertha JM, Mitchell, Amir |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725501/ https://www.ncbi.nlm.nih.gov/pubmed/33252330 http://dx.doi.org/10.7554/eLife.59831 |
Ejemplares similares
-
Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy in co-cultured cancer cells
por: Sayin, Serkan, et al.
Publicado: (2023) -
Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities
por: Narasimhan, Kamesh, et al.
Publicado: (2015) -
Systems‐level transcriptional regulation of Caenorhabditis elegans metabolism
por: Nanda, Shivani, et al.
Publicado: (2023) -
A regulatory cascade of three transcription factors in a single specific neuron, DVC, in Caenorhabditis elegans
por: Feng, Huiyun, et al.
Publicado: (2012) -
Modeling tissue‐relevant Caenorhabditis elegans metabolism at network, pathway, reaction, and metabolite levels
por: Yilmaz, Lutfu Safak, et al.
Publicado: (2020)