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Transgenic Tarantula Toxin: A novel tool to study mechanosensitive ion channels in Drosophila

The tarantula venom toxin GsMTx4 is the only known specific inhibitor of cation-selective mechanosensitive ion channels (MSCs). Its specificity, potency, and ease of use on isolated tissues and cells have made it a powerful pharmacological tool to identify and probe the physiological function of MSC...

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Detalles Bibliográficos
Autores principales: Beqja, Denis, Haidar, Sunna, Nikolaev, Mihail, Shen, Yilan, Denholm, Barry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725602/
https://www.ncbi.nlm.nih.gov/pubmed/32991864
http://dx.doi.org/10.1016/j.jinsphys.2020.104116