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Drosophila MICOS knockdown impairs mitochondrial structure and function and promotes mitophagy in muscle tissue

The mitochondrial contact site and cristae organizing system (MICOS) is a multi-protein interaction hub that helps define mitochondrial ultrastructure. While the functional importance of MICOS is mostly characterized in yeast and mammalian cells in culture, the contributions of MICOS to tissue homeo...

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Detalles Bibliográficos
Autores principales: Wang, Li-jie, Hsu, Tian, Lin, Hsiang-ling, Fu, Chi-yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725604/
https://www.ncbi.nlm.nih.gov/pubmed/33268479
http://dx.doi.org/10.1242/bio.054262