Immunostimulatory oncolytic virotherapy for multiple myeloma targeting 4-1BB and/or CD40

Multiple myeloma (MM) is a plasma cell malignancy that is characterized by immune dysregulation. MM is commonly treated with immunomodulating agents, but still remains incurable. Herein, we proposed and evaluated immunostimulatory Lokon oncolytic adenoviruses (LOAd) for MM treatment. LOAd viruses ar...

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Detalles Bibliográficos
Autores principales: Wenthe, Jessica, Naseri, Sedigheh, Hellström, Ann-Charlotte, Wiklund, Helena Jernberg, Eriksson, Emma, Loskog, Angelica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725669/
https://www.ncbi.nlm.nih.gov/pubmed/32355275
http://dx.doi.org/10.1038/s41417-020-0176-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725669/
https://www.ncbi.nlm.nih.gov/pubmed/32355275
http://dx.doi.org/10.1038/s41417-020-0176-9

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