Cargando…
Improvement of muscular atrophy by AAV–SaCas9-mediated myostatin gene editing in aged mice
Muscle mass and area usually decrease with age, and this phenomenon is known as sarcopenia. This age-related atrophy correlates with insufficient levels of muscle cells differentiate and proliferate regulated by the TGF-β signaling pathway and the expression of E3s ubiquitin-protein ligase by the ag...
Autores principales: | Weng, Shaoting, Gao, Feng, Wang, Juan, Li, Xingyu, Chu, Beibei, Wang, Jiang, Yang, Guoyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group US
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725670/ https://www.ncbi.nlm.nih.gov/pubmed/32398787 http://dx.doi.org/10.1038/s41417-020-0178-7 |
Ejemplares similares
-
Construction of a rAAV-SaCas9 system expressing eGFP and its application to improve muscle mass
por: Weng, Shaoting, et al.
Publicado: (2021) -
Editing Citrus Genome via SaCas9/sgRNA System
por: Jia, Hongge, et al.
Publicado: (2017) -
Expanding CRISPR/Cas9 Genome Editing Capacity in Zebrafish Using SaCas9
por: Feng, Yan, et al.
Publicado: (2016) -
Inhibition of HBV Expression in HBV Transgenic Mice Using AAV-Delivered CRISPR-SaCas9
por: Li, Hao, et al.
Publicado: (2018) -
Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion Neurons
por: Chen, Yuxi, et al.
Publicado: (2020)