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Plasmodium falciparum DHFR and DHPS Mutations Are Associated With HIV-1 Co-Infection and a Novel DHPS Mutation I504T Is Identified in Western Kenya

Antifolate resistance is significant in Kenya and presumed to result from extensive use and cross-resistance between antifolate antimalarials and antibiotics, including cotrimoxazole/Bactrim used for HIV-1 chemotherapy. However, little is known about antifolate-resistant malaria in the context of ne...

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Detalles Bibliográficos
Autores principales: Torrevillas, Brandi K., Garrison, Sarah M., McKeeken, Alexander J., Patel, Dharmeshkumar, Van Leuven, James T., Dizon, Nathaniel I., Rivas, Karina I., Hathaway, Nicholas J., Bailey, Jeffrey A., Waitumbi, John N., Kifude, Carolyne M., Oyieko, Janet, Stewart, V. Ann, Luckhart, Shirley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725689/
https://www.ncbi.nlm.nih.gov/pubmed/33324580
http://dx.doi.org/10.3389/fcimb.2020.600112