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A Neurotoxic Ménage-à-trois: Glutamate, Calcium, and Zinc in the Excitotoxic Cascade

Fifty years ago, the seminal work by John Olney provided the first evidence of the neurotoxic properties of the excitatory neurotransmitter glutamate. A process hereafter termed excitotoxicity. Since then, glutamate-driven neuronal death has been linked to several acute and chronic neurological cond...

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Detalles Bibliográficos
Autores principales: Granzotto, Alberto, Canzoniero, Lorella M. T., Sensi, Stefano L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725690/
https://www.ncbi.nlm.nih.gov/pubmed/33324162
http://dx.doi.org/10.3389/fnmol.2020.600089