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Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo

In a secondary dengue virus (DENV) infection, the presence of non-neutralizing antibodies (Abs), developed during a previous infection with a different DENV serotype, is thought to worsen clinical outcomes by enhancing viral production. This phenomenon is called antibody-dependent enhancement (ADE)...

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Detalles Bibliográficos
Autores principales: Kurosu, Takeshi, Hanabara, Keiko, Asai, Azusa, Pambudi, Sabar, Phanthanawiboon, Supranee, Omokoko, Magot Diata, Ono, Ken-ichiro, Saijo, Masayuki, Ramasoota, Pongrama, Ikuta, Kazuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725774/
https://www.ncbi.nlm.nih.gov/pubmed/33299049
http://dx.doi.org/10.1038/s41598-020-78639-x