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Chimeric flavivirus enables evaluation of antibodies against dengue virus envelope protein in vitro and in vivo
In a secondary dengue virus (DENV) infection, the presence of non-neutralizing antibodies (Abs), developed during a previous infection with a different DENV serotype, is thought to worsen clinical outcomes by enhancing viral production. This phenomenon is called antibody-dependent enhancement (ADE)...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725774/ https://www.ncbi.nlm.nih.gov/pubmed/33299049 http://dx.doi.org/10.1038/s41598-020-78639-x |