TRIB3 promotes MYC-associated lymphoma development through suppression of UBE3B-mediated MYC degradation

The transcription factor MYC is deregulated in almost all human cancers, especially in aggressive lymphomas, through chromosomal translocation, amplification, and transcription hyperactivation. Here, we report that high expression of tribbles homologue 3 (TRIB3) positively correlates with elevated M...

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Detalles Bibliográficos
Autores principales: Li, Ke, Wang, Feng, Yang, Zhao-na, Zhang, Ting-ting, Yuan, Yu-fen, Zhao, Chen-xi, Yeerjiang, Zaiwuli, Cui, Bing, Hua, Fang, Lv, Xiao-xi, Zhang, Xiao-wei, Yu, Jiao-jiao, Liu, Shan-shan, Yu, Jin-mei, Shang, Shuang, Xiao, Yang, Hu, Zhuo-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725785/
https://www.ncbi.nlm.nih.gov/pubmed/33298911
http://dx.doi.org/10.1038/s41467-020-20107-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725785/
https://www.ncbi.nlm.nih.gov/pubmed/33298911
http://dx.doi.org/10.1038/s41467-020-20107-1

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