Fused isoselenazolium salts suppress breast cancer cell growth by dramatic increase in pyruvate-dependent mitochondrial ROS production

The development of targeted drugs for the treatment of cancer remains an unmet medical need. This study was designed to investigate the mechanism underlying breast cancer cell growth suppression caused by fused isoselenazolium salts. The ability to suppress the proliferation of malignant and normal...

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Detalles Bibliográficos
Autores principales: Makrecka-Kuka, Marina, Dimitrijevs, Pavels, Domracheva, Ilona, Jaudzems, Kristaps, Dambrova, Maija, Arsenyan, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725824/
https://www.ncbi.nlm.nih.gov/pubmed/33299068
http://dx.doi.org/10.1038/s41598-020-78620-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725824/
https://www.ncbi.nlm.nih.gov/pubmed/33299068
http://dx.doi.org/10.1038/s41598-020-78620-8

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