HIF1A signaling selectively supports proliferation of breast cancer in the brain

Blood-borne metastasis to the brain is a major complication of breast cancer, but cellular pathways that enable cancer cells to selectively grow in the brain microenvironment are poorly understood. We find that cultured circulating tumor cells (CTCs), derived from blood samples of women with advance...

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Detalles Bibliográficos
Autores principales: Ebright, Richard Y., Zachariah, Marcus A., Micalizzi, Douglas S., Wittner, Ben S., Niederhoffer, Kira L., Nieman, Linda T., Chirn, Brian, Wiley, Devon F., Wesley, Benjamin, Shaw, Brian, Nieblas-Bedolla, Edwin, Atlas, Lian, Szabolcs, Annamaria, Iafrate, Anthony J., Toner, Mehmet, Ting, David T., Brastianos, Priscilla K., Haber, Daniel A., Maheswaran, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725834/
https://www.ncbi.nlm.nih.gov/pubmed/33298946
http://dx.doi.org/10.1038/s41467-020-20144-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725834/
https://www.ncbi.nlm.nih.gov/pubmed/33298946
http://dx.doi.org/10.1038/s41467-020-20144-w

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