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HIF1A signaling selectively supports proliferation of breast cancer in the brain
Blood-borne metastasis to the brain is a major complication of breast cancer, but cellular pathways that enable cancer cells to selectively grow in the brain microenvironment are poorly understood. We find that cultured circulating tumor cells (CTCs), derived from blood samples of women with advance...
Autores principales: | Ebright, Richard Y., Zachariah, Marcus A., Micalizzi, Douglas S., Wittner, Ben S., Niederhoffer, Kira L., Nieman, Linda T., Chirn, Brian, Wiley, Devon F., Wesley, Benjamin, Shaw, Brian, Nieblas-Bedolla, Edwin, Atlas, Lian, Szabolcs, Annamaria, Iafrate, Anthony J., Toner, Mehmet, Ting, David T., Brastianos, Priscilla K., Haber, Daniel A., Maheswaran, Shyamala |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725834/ https://www.ncbi.nlm.nih.gov/pubmed/33298946 http://dx.doi.org/10.1038/s41467-020-20144-w |
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