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Pan-cancer analysis of genomic properties and clinical outcome associated with tumor tertiary lymphoid structure

How the genomic landscape of a tumor shapes the formation of tertiary lymphoid structure (TLS) and how might TLS alter the clinical outcome or response to immunotherapy had not been systematically explored. Utilizing the genomic and transcriptome data of solid tumors on TCGA, we quantified TLS based...

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Detalles Bibliográficos
Autores principales: Lin, Ziying, Huang, Lixia, Li, ShaoLi, Gu, Jincui, Cui, Xiaoxian, Zhou, Yanbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725838/
https://www.ncbi.nlm.nih.gov/pubmed/33299035
http://dx.doi.org/10.1038/s41598-020-78560-3