Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant

Developmental and epileptic encephalopathies (DEE) are a group of severe epilepsies that usually present with intractable seizures, developmental delay, and often have elevated risk for premature mortality. Numerous genes have been identified as a monogenic cause of DEE, including KCNB1. The voltage...

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Detalles Bibliográficos
Autores principales: Hawkins, Nicole A., Misra, Sunita N, Jurado, Manuel, Kang, Seok Kyu, Vierra, Nicholas C., Nguyen, Kimberly, Wren, Lisa, George, Alfred L., Trimmer, James S., Kearney, Jennifer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725922/
https://www.ncbi.nlm.nih.gov/pubmed/33132203
http://dx.doi.org/10.1016/j.nbd.2020.105141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7725922/
https://www.ncbi.nlm.nih.gov/pubmed/33132203
http://dx.doi.org/10.1016/j.nbd.2020.105141

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