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Tunable dynamics of B cell selection in gut germinal centers

Germinal centers (GCs), structures normally associated with B cell immunoglobulin (Ig) hypermutation and development of high-affinity antibodies upon infection or immunization, are present in gut-associated lymphoid organs of humans and mice under steady state. Gut-associated (ga)GCs can support ant...

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Detalles Bibliográficos
Autores principales: Nowosad, Carla R., Mesin, Luka, Castro, Tiago B.R., Wichmann, Christopher, Donaldson, Gregory P., Araki, Tatsuya, Schiepers, Ariën, Lockhart, Ainsley A. K., Bilate, Angelina M., Mucida, Daniel, Victora, Gabriel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726069/
https://www.ncbi.nlm.nih.gov/pubmed/33116306
http://dx.doi.org/10.1038/s41586-020-2865-9