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Tunable dynamics of B cell selection in gut germinal centers
Germinal centers (GCs), structures normally associated with B cell immunoglobulin (Ig) hypermutation and development of high-affinity antibodies upon infection or immunization, are present in gut-associated lymphoid organs of humans and mice under steady state. Gut-associated (ga)GCs can support ant...
Autores principales: | Nowosad, Carla R., Mesin, Luka, Castro, Tiago B.R., Wichmann, Christopher, Donaldson, Gregory P., Araki, Tatsuya, Schiepers, Ariën, Lockhart, Ainsley A. K., Bilate, Angelina M., Mucida, Daniel, Victora, Gabriel D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726069/ https://www.ncbi.nlm.nih.gov/pubmed/33116306 http://dx.doi.org/10.1038/s41586-020-2865-9 |
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