Whole brain proton irradiation in adult Sprague Dawley rats produces dose dependent and non-dependent cognitive, behavioral, and dopaminergic effects

Proton radiotherapy causes less off-target effects than X-rays but is not without effect. To reduce adverse effects of proton radiotherapy, a model of cognitive deficits from conventional proton exposure is needed. We developed a model emphasizing multiple cognitive outcomes. Adult male rats (10/gro...

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Detalles Bibliográficos
Autores principales: Williams, Michael T., Sugimoto, Chiho, Regan, Samantha L., Pitzer, Emily M., Fritz, Adam L., Mascia, Anthony E., Sertorio, Mathieu, Vatner, Ralph E., Perentesis, John P., Vorhees, Charles V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726106/
https://www.ncbi.nlm.nih.gov/pubmed/33299021
http://dx.doi.org/10.1038/s41598-020-78128-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726106/
https://www.ncbi.nlm.nih.gov/pubmed/33299021
http://dx.doi.org/10.1038/s41598-020-78128-1

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