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Learning-Dependent Dendritic Spine Plasticity Is Reduced in the Aged Mouse Cortex

Aging is accompanied by a progressive decrease in learning and memory function. Synaptic loss, one of the hallmarks of normal aging, likely plays an important role in age-related cognitive decline. But little is known about the impact of advanced age on synaptic plasticity and neuronal function in v...

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Detalles Bibliográficos
Autores principales: Huang, Lianyan, Zhou, Hang, Chen, Kai, Chen, Xiao, Yang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726160/
https://www.ncbi.nlm.nih.gov/pubmed/33324172
http://dx.doi.org/10.3389/fncir.2020.581435