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Cone Photoreceptor Degeneration and Neuroinflammation in the Zebrafish Bardet-Biedl Syndrome 2 (bbs2) Mutant Does Not Lead to Retinal Regeneration

Bardet-Biedl syndrome (BBS) is a heterogeneous and pleiotropic autosomal recessive disorder characterized by obesity, retinal degeneration, polydactyly, renal dysfunction, and mental retardation. BBS results from defects in primary and sensory cilia. Mutations in 21 genes have been linked to BBS and...

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Detalles Bibliográficos
Autores principales: Song, Ping, Fogerty, Joseph, Cianciolo, Lauren T., Stupay, Rachel, Perkins, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726229/
https://www.ncbi.nlm.nih.gov/pubmed/33324636
http://dx.doi.org/10.3389/fcell.2020.578528