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mTORC1 Transcriptional Regulation of Ribosome Subunits, Protein Synthesis, and Molecular Transport in Primary Human Trophoblast Cells

Mechanistic Target of Rapamycin Complex 1 (mTORC1) serves as positive regulator of placental nutrient transport and mitochondrial respiration. The role of mTORC1 signaling in modulating other placental functions is largely unexplored. We used gene array following silencing of raptor to identify gene...

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Detalles Bibliográficos
Autores principales: Rosario, Fredrick J., Powell, Theresa L., Gupta, Madhulika B., Cox, Laura, Jansson, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726231/
https://www.ncbi.nlm.nih.gov/pubmed/33324640
http://dx.doi.org/10.3389/fcell.2020.583801