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Negative Clinical Evolution in COVID-19 Patients Is Frequently Accompanied With an Increased Proportion of Undifferentiated Th Cells and a Strong Underrepresentation of the Th1 Subset

The severity of SARS-CoV-2 infection has been related to uncontrolled inflammatory innate responses and impaired adaptive immune responses mostly due to exhausted T lymphocytes and lymphopenia. In this work we have characterized the nature of the lymphopenia and demonstrate a set of factors that hin...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Bautista, Juan Francisco, Rodriguez-Nicolas, Antonio, Rosales-Castillo, Antonio, Jiménez, Pilar, Garrido, Federico, Anderson, Per, Ruiz-Cabello, Francisco, López-Ruz, Miguel Ángel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726249/
https://www.ncbi.nlm.nih.gov/pubmed/33324414
http://dx.doi.org/10.3389/fimmu.2020.596553