Whole-Brain Three-Dimensional Profiling Reveals Brain Region Specific Axon Vulnerability in 5xFAD Mouse Model

Axonopathy is a pathological feature observed in both Alzheimer’s disease (AD) patients and animal models. However, identifying the temporal and regional progression of axonopathy during AD development remains elusive. Using the fluorescence micro-optical sectioning tomography system, we acquired wh...

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Detalles Bibliográficos
Autores principales: Zhang, Jianping, Long, Ben, Li, Anan, Sun, Qingtao, Tian, Jiaojiao, Luo, Ting, Ding, Zhangheng, Gong, Hui, Li, Xiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroanatomy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726261/
https://www.ncbi.nlm.nih.gov/pubmed/33324177
http://dx.doi.org/10.3389/fnana.2020.608177

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726261/
https://www.ncbi.nlm.nih.gov/pubmed/33324177
http://dx.doi.org/10.3389/fnana.2020.608177

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