Nebulised surfactant for the treatment of severe COVID-19 in adults (COV-Surf): A structured summary of a study protocol for a randomized controlled trial

OBJECTIVES: SARS-Cov-2 virus preferentially binds to the Angiotensin Converting Enzyme 2 (ACE2) on alveolar epithelial type II cells, initiating an inflammatory response and tissue damage which may impair surfactant synthesis contributing to alveolar collapse, worsening hypoxia and leading to respir...

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Detalles Bibliográficos
Autores principales: Dushianthan, Ahilanandan, Clark, Howard, Madsen, Jens, Mogg, Robin, Matthews, Lewis, Berry, Lee, de la Serna, Jorge Bernardino, Batchelor, James, Brealey, David, Hussell, Tracy, Porter, Joanna, Djukanovic, Ratko, Feelisch, Martin, Postle, Anthony, Grocott, Michael P. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726271/
https://www.ncbi.nlm.nih.gov/pubmed/33302976
http://dx.doi.org/10.1186/s13063-020-04944-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726271/
https://www.ncbi.nlm.nih.gov/pubmed/33302976
http://dx.doi.org/10.1186/s13063-020-04944-5

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