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Specific Targeting of Lymphoma Cells Using Semisynthetic Anti-Idiotype Shark Antibodies

The B-cell receptor (BCR) is a key player of the adaptive immune system. It is a unique part of immunoglobulin (Ig) molecules expressed on the surface of B cells. In case of many B-cell lymphomas, the tumor cells express a tumor-specific and functionally active BCR, also known as idiotype. Utilizing...

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Detalles Bibliográficos
Autores principales: Macarrón Palacios, Arturo, Grzeschik, Julius, Deweid, Lukas, Krah, Simon, Zielonka, Stefan, Rösner, Thies, Peipp, Matthias, Valerius, Thomas, Kolmar, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726437/
https://www.ncbi.nlm.nih.gov/pubmed/33324393
http://dx.doi.org/10.3389/fimmu.2020.560244