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Inhibition of Tryptophan Hydroxylases and Monoamine Oxidase-A by the Proton Pump Inhibitor, Omeprazole—In Vitro and In Vivo Investigations

Serotonin (5-HT) is a hormone and neurotransmitter that modulates neural activity as well as a wide range of other physiological processes including cardiovascular function, bowel motility, and platelet aggregation. 5-HT synthesis is catalyzed by tryptophan hydroxylase (TPH) which exists as two dist...

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Detalles Bibliográficos
Autores principales: Betari, Nibal, Sahlholm, Kristoffer, Morató, Xavier, Godoy-Marín, Héctor, Jáuregui, Olga, Teigen, Knut, Ciruela, Francisco, Haavik, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726444/
https://www.ncbi.nlm.nih.gov/pubmed/33324221
http://dx.doi.org/10.3389/fphar.2020.593416