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Lack of PTEN in osteocytes increases circulating phosphate concentrations by decreasing intact fibroblast growth factor 23 levels

Fibroblast growth factor 23 (FGF23) has been centric to the regulation of phosphate (Pi) metabolism; however, the regulatory network of FGF23 in osteocytes has not yet been defined in detail. We herein investigated the role of PTEN (phosphatase and tensin homolog deleted from chromosome 10) in this...

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Detalles Bibliográficos
Autores principales: Kawai, Masanobu, Kinoshita, Saori, Ozono, Keiichi, Michigami, Toshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726559/
https://www.ncbi.nlm.nih.gov/pubmed/33299044
http://dx.doi.org/10.1038/s41598-020-78692-6