Thermostability profiling of MHC-bound peptides: a new dimension in immunopeptidomics and aid for immunotherapy design

The features of peptide antigens that contribute to their immunogenicity are not well understood. Although the stability of peptide-MHC (pMHC) is known to be important, current assays assess this interaction only for peptides in isolation and not in the context of natural antigen processing and pres...

Descripción completa

Detalles Bibliográficos
Autores principales: Jappe, Emma C., Garde, Christian, Ramarathinam, Sri H., Passantino, Ethan, Illing, Patricia T., Mifsud, Nicole A., Trolle, Thomas, Kringelum, Jens V., Croft, Nathan P., Purcell, Anthony W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726561/
https://www.ncbi.nlm.nih.gov/pubmed/33298915
http://dx.doi.org/10.1038/s41467-020-20166-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726561/
https://www.ncbi.nlm.nih.gov/pubmed/33298915
http://dx.doi.org/10.1038/s41467-020-20166-4

Ejemplares similares